WEDINOS DAN 24/7 Public Health Wales Welsh Government Naloxone saves lives


Type Psychoactive
Legal Status Conditional
Thienodiazepine drug which is a benzodiazepine analogue. Etizolam is used for therapeutic purposes almost exclusively in Japan and it is not approved for human use in other countries.
Short Term Effects
Etizolam has the full range of group-specific benzodiazepine effects: anxiolytic, sedative, hypnotic, anticonvulsant, and muscle relaxant. It is 6-10 times more potent than diazepam (WHO expert committee on drug dependence, 1991). Benzodiazepines commonly cause drowsiness, ataxia, dysarthria and nystagmus. Coma, hypotension, bradycardia and respiratory depression occasionally occur but are seldom serious if these drugs are taken alone. Coma usually lasts only a few hours but may be prolonged in elderly patients. Benzodiazepine respiratory depressant effects are more serious in patients with severe chronic obstructive airways disease. Severe effects in overdose also include rhabdomyolysis and hypothermia. Co-ingestion of alcohol and other central nervous system depressants potentiates the effects of benzodiazepines and can increase toxicity.